A Rare Complications of Sickle Cell Disease: Empyema and Chronic Subdural Hematoma



Abstract Views
333

Downloads
315

Citations

Share

##plugins.themes.bootstrap3.article.sidebar##

Submitted Jan 24, 2021
Published Feb 22, 2021
10.24018/clinicmed.2021.2.1.16

Abstract viewed = 333 times

Table of Contents

##plugins.themes.bootstrap3.article.main##

Sickle cell disease is a hemoglobinopathy responsible for many complications that are sometimes frightening. Brain damage is part of one of the complications that can affect the vital and/or functional prognosis of patients.    We report two cases of neurological complications, patients with known homozygous sickle cell disease, admitted to the Resuscitation Service of the JRA University Hospital for neurological deficit of recent appearance. One presented a spontaneous bilateral chronic bilateral subdural hematoma, and the other an extradural empyema diagnosed on brain scan. The patients benefited from a neurosurgical intervention with favorable postoperative outcomes, marked by an improvement in neurological symptoms. This form of complication is relatively rare in patients with sickle cell disease. It is favoured by repeated vaso-occlusive crises responsible for vascular fragility following repeated ischemia and inflammatory phenomena. The surgical indication depends on the clinical condition and the radiological aspect

Keywords: empyema sickle cell disease subdural hematoma surgery

References

  1. Mattioni S, Stojanovic KS, Girot R, Lionnet F. La drépanocytose en France. Rev Francoph des Lab. 2016 Avril; 487:61-6.
     Google Scholar
  2. RAKOTONDRASOA N. Profil radiologique des patients drépanocytaires vus au Service d’imagerie du CHU Joseph RAVOHANGY ANDRIANAVALONA Antananarivo [Thèse]. Médecine humaine: Antananarivo: 2015.
     Google Scholar
  3. BarabeP, Charles D. L'hémolyse chronique et ses mécanismes dans la drépanocytose. Méd Trop. 1978; 38: 151 – 4.
     Google Scholar
  4. Gill FM, Sleeper LA, Weiner SJ, Brown AK, Bellevue R, Grover R, et al. Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperativestudy of sicklecelldisease. Blood 1995 ; 86 : 776-83.
     Google Scholar
  5. Emmanuelle L, Phippe R. Prévention des infections chez l’enfant drépanocytaire.Développement et Santé.2006 Aout 2 ; 182.
     Google Scholar
  6. Philippe R. Infections et drépanocytose. Développement et Santé. 1982 fevr 26 ; 182.
     Google Scholar
  7. Ohene-Frempong K, Weiner SJ, Sleeper LA, Miller ST, Embury S, MoohrJW , et al. Cerebrovascular accidents in sickle cell disease: rates and risk factors. Pub med. 1998 Jan 1; 91(1): 288-94.
     Google Scholar
  8. Strouse J, Hubert M, Debaun M, Jordan L, Casela J. Primary hemorrhagic stroke in children with sickle cell disease is associated with recent transfuion and use of corticoids. Pub Med 2006 Nov; 118(5):1916-24.
     Google Scholar
  9. Cabon I, Hladky JP, Lambillotte A, Cotton A, Dhellemmes P. Uncommon etiology of extradural hematoma. Pub Med. 1997; 43(3):173-6.
     Google Scholar


Most read articles by the same author(s)