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Introduction: Anaemia in pregnancy is a global public health problem causing both maternal and perinatal morbidities and mortalities. Prevalent rates vary from one geopolitical region to the other. Efforts have been made to reduce this condition during pregnancy through the use of haematinics and other interventions. However, despite all the efforts put in place, pregnant women still present with this condition. This study was carried out to find out its prevalence rate and the factors responsible for it.

Materials and Methods: It was a cross-sectional institutional based study carried out at the antenatal clinic of the University of Medical Sciences Teaching Hospital Complex, Akure, Ondo State, South West, Nigeria. The study used a systematic sampling to recruit 400 antenatal clinic patients over a period of 16weeks starting from the 16th of August to 16th of December 2022.The women were interviewed with copies of a structured questionnaire administered by trained research doctors who also helped in the collection of the blood samples. About 3mls of venous blood was collected from the antecubital vein using plastic disposable syringes into sample bottles containing ethylene diamine-tetra acetic acid (EDTA) and the bottles labelled accordingly. Packed cell volume and red cell morphology were done for the women at the time of recruitment. Data obtained were analysed using the Statistical Package for Social Sciences (SPSS Version 22). Descriptive statistics were computed for all relevant variables, Chi Square test and Multivariate logistic regression were used to test for association and possible risk factors for anaemia. The level of significance was set at ???? < 0.05.

Results: Most of the women were within 30years- 39years (51.2%, 205) with a mean age of 31.61years±5.37years. Most of them were married (97.3%, 389), were Christians (94.5%, 378), were Yorubas (82.8%, 331), were traders (40.3%, 161), had tertiary level of education (68.8%, 275) and lived in the urban areas of Ondo State (89.5%,358). Most had their first menses between the ages of 10 to 15 years (79.2%, 317) with a mean age of 14.24 ± 2.12 years. Majority had inter- pregnancy interval of ≤ 2 years (53.7%, 215). There was no history of bleeding in most of the women (91.5%, 366), many of them were in the third trimester of their pregnancy (64.1%, 257) with a mean gestational age of 28.83 ± 6.91 weeks. The prevalence of anaemia among the study participants was 40.0% (160/400) while 60% (240/400) were not anaemic. Among the participants who were anaemic, 77.5% (124/160) had mild anaemia, 22.5% (36/160) had moderate anaemia while none had severe anaemia. The only risk factors identified to be responsible for anaemia among the women were high parity and being in the third trimester of pregnancy.

Conclusion: This study showed that the prevalence of anaemia is still high among our women mostly occurring among women of high parity and in the third trimester of pregnancy. Efforts must be intensified to address this condition through the use of haematinics which can be started pre-conception and adequate counselling on the need to fully recover from the effects of one pregnancy before embarking on another.

References

  1. Akhtar M, Hassan I. Severe anaemia during late pregnancy. Case Report Obstet Gynecol. 2012; 2012: 3.
     Google Scholar
  2. Hassan A, Mamman AI, Adaji S, Musa B, Kene S. Anaemia and iron deficiency in pregnant women in Zaria, Nigeria. Sub-Saharan African Journal of Medicine. 2014; 1: 36-39.
     Google Scholar
  3. World Health Organization (WHO). Worldwide Prevalence of Anaemia 1993-2005. WHO Global Database on Anaemia. Geneva, Switzerland: WHO Press. 2008: 7-8.
     Google Scholar
  4. Salhan S, Tripathi V, Singh R, Gaikwad HS. Evaluation of haematological parameters in partial exchange and packed cell transfusion in treatment of severe anemia in pregnancy. Anemia Journal. 2012; 2012: 608-658.
     Google Scholar
  5. World Health Organization (WHO), Centre for Disease Control and Prevention. Assessing the iron status of populations. 2007.
     Google Scholar
  6. Bukar M, Audu BM, Sadauki HM, Elnafaty AU, Mairiga AG. Prevalence of iron deficiency and megaloblastic anaemia at booking in a secondary Health facilty in North Eastern Nigeria. Nigerian Journal of Medicine. 2009; 50(2): 33-37.
     Google Scholar
  7. Geelhoed D, Agadzi F, Visser L. Severe anaemia in pregnancy in rural Ghana: a case-control study of causes and management. Acta Obstetricia et Gynecologica Scandinavica. 2006; 85(10): 1165-1171.
     Google Scholar
  8. World Health Organization (WHO). The World Health Report. Geneva,Switzerland: WHO Press. 2005.
     Google Scholar
  9. Orish VN, Onyeabor OS, Boampong JN, Acquah S, Sanyaolu AO, Iriemenam NC. The effects of malaria and HIV co-infection on hemoglobin levels among pregnant women in Sekondi-Takoradi, Ghana. Int J Gynecol Obstet. 2013; 120(3): 236-9.
     Google Scholar
  10. Olatunbosun OA, Abasiattai AM, Bassey EA, James RS, Ibanga G, and Morgan A. Prevalence of anaemia among pregnant women at booking in the university of uyo teaching hospital, uyo, Nigeria. BioMed Research International. 2014.
     Google Scholar
  11. Lee AI, Okam MM. Anaemia in pregnancy. Hematol Oncol Clin North Am. 2001; 25: 241-259.
     Google Scholar
  12. Adinma JIB, Ikechebelu JI, Onyejimbe UN, Amilo G, Adinma E. Influence of antenatal care on the haematocrit Value of pregnant Nigerian Igbo Women. Tropical Journal of Obstetrics and Gynaecology. 2002; 19(2): 68-70.
     Google Scholar
  13. Anorlu RI, Oluwole AA, Abudu OO. Sociodemographic factors in anaemia in pregnancy at booking in Lagos, Nigeria. Journal of Obstetrics and Gynaecology. 2006; 26(8): 773-776.
     Google Scholar
  14. Dim CC, Onah HE. The prevalence of anaemia among pregnant women at booking in Enugu, South Eastern Nigeria. Medscape General Medicine. 2007; 9(3): 11.
     Google Scholar
  15. World Health Organization (WHO). The Prevalence of Anaemia in Women: A Tabulation of Available Information. Geneva, Switzerland: WHO Press. 1992.
     Google Scholar
  16. Liyew AM, Tesema GA, Alamneh TS, Worku MG, Teshale AB, Alem AZ, et al. Prevalence and determinants of anaemia among pregnant women in East Africa; A multi-levelanalysis of recent Demographic and Health Surveys. PLoS ONE. 2021; 16(4): e0250560.
     Google Scholar
  17. Oladipo AR, Falana AO, Adegoke O, Sambo A, Kungu J. Prevalence of anaemia among pregnant women and its determinants in Northern Nigeria. Gynecol Obstet Res Open J. 2005; 132-139.
     Google Scholar
  18. Ayoya MA. Determinants of anaemia among pregnant women in Mali. Food and Nutrition Bulletin. 2006; 27(1): 3-11.
     Google Scholar
  19. Rajamouli J. Study on Prevalence of Anaemia among Pregnant Women attending Antenatal Clinic at Rural Health Training Centre (RHTC) and Chalmeda Anand Rao Institute of Medical Sciences Teaching Hospital, Karimnagar, Telangana, India. International Journal of Contemporary Medical Research. 2016; 3(8): 43-50.
     Google Scholar
  20. Adam I, Ibrahim Y, Elhardello O. Prevalence, types and determinants of anaemia among pregnant women in Sudan: a systematic review and meta-analysis. BMC Hematology. 2018; 18(1): 1-8.
     Google Scholar
  21. Baig-Ansari N. Anaemia prevalence and risk factors in pregnant women in an urban area of Pakistan. Food and Nutrition Bulletin. 2008; 29(2): 132-139.
     Google Scholar
  22. Chakona G, Shackleton C. Food Taboos and Cultural Beliefs Influence Food Choice and Dietary Preferences among Pregnant Women in the Eastern Cape, South Africa. Nutrients. 2019; 11(11): 2668.
     Google Scholar
  23. Oni T, Unwin N. Why the communicable/non-communicable disease dichotomy is problematic for public health control strategies: implications of multimorbidity for health systems in an era of health transition. International Health. 2015; 7(6): 390-399.
     Google Scholar
  24. Aluka C, Amadi AN, Kamanu CI, Feyi-Waboso PA. Anaemia in pregnancy in Abia State University Teaching Hospital, Aba. Journal of Medical Investigation Practition (JOMIP). 2001; 2: 58-61.
     Google Scholar
  25. Adinma JIB, Ikechebelu JI, Onyejimbe UN, Amilo G, Adinma E. Influence of antenatal care on the haematocrit value of pregnant Nigerian Igbo women. Trop J Obstet Gynaecol. 2002; 19: 68-70.
     Google Scholar
  26. Aimakhu CO, Olayemi O. Maternal haematocrit and pregnancy outcome in Nigerian women. West Afr J Med. 2003; 22: 18-21.
     Google Scholar
  27. Bassi AP, Idoko L, Dibigbo-Ibeaji NM, Godwin AO, Seljul RMC, Olugbenga OT, et al. Prevalence of anaemia in pregnancy among women visiting antenatal clinic in bingham University Teaching Hospital Jos, Nigeria. Clinical Medicine Research. 2016; 5: 52-62.
     Google Scholar
  28. Mohammed YG, Emmanue AU. The pattern of anaemia in Northern Nigerian pregnant women. Journal of Medicine and Medical Sciences. 2013; 4: 319-323.
     Google Scholar
  29. Owolabi MO, Owolabi AO, OlaOlorun DA. Sociodemographic factors in anaemia in pregnancy in south-western Nigeria. S Afri Fam Pract. 2012; 54: 222-227.
     Google Scholar
  30. Nonterah EA, Adomolga E, Yidana A, Alhassan M, Kagura J, Yidana A, et al. Descriptive epidemiology of anaemia among pregnant women initiating antenatal care in rural Northern Ghana. African Journal ofPrimary Health Care & Family Medicine. 2019; 11(1): 1-7.
     Google Scholar
  31. Al-Farsi YM, Brooks DR, Werher MM, Cabral AJ, Al-Shafei MA, Wallenburg HC. Effects of high parity on occurrence of anaemia in pregnancy: a cohort study. BMC Pregnancy Childbirth. 2011; 11(1): 7.
     Google Scholar
  32. Chowdhury HA, Ahmed KR, Jebumessa F, Aker J, Hossain S, Shahjahan M. Factors associated with maternal anaemia among pregnant women in Dhaka city. BMC Women’s Health. 2015; 15: 77.
     Google Scholar
  33. Stephen G, Mgongo M, Hashim TH, Katanga J, Stray- Pedersen B, Msuya SE. Anaemia in pregnancy: prevalence, risk factors, and adverse perinatal outcomes in Northern Tanzania. Anaemia. 2018.
     Google Scholar