Diagnostic Difficulties and Management of Childhood Lymphoma: A Case Report


  •   M. Tien Yu Song

  •   A. Ralitera

  •   C. U. Rasolofoson

  •   J. S. Bemora

  •   E. C. Rasolonjatovo

  •   W. Ratovondrainy

  •   R. Mamiarisoa

  •   C. Andriamamonjy


Primary dural lymphoma is a rare pathology, it is part of the malignant lymphoma of the central nervous system and it can reach the extradural or subdural space. We report a case of a little boy of three years and two months admitted to the Department of Neurosurgery CHU JRA for multiple swellings in the scalp associated with an altered general condition. The CT scan revealed a multiple extra-axial expansive process with retro-orbital extension responsible for an important exophthalmos as well as at the scalp level. Anatomopathological examination of the dura mater biopsy revealed a malignant non-Hodgkin's small cell lymphoma. The patient underwent chemotherapy of 05 sessions and the evolution was marked by the persistence of the symptoms. The post chemotherapy brain scan showed considerable extension of the lesions. The next step would be radiotherapy.

Keywords: Chemotherapy, Dural lymphoma, Radiotherapy, Small cell non-Hodgkin's lymphoma.


Randriamampianina T, Rahantamalala MI, Dinafanomezana HR, Rakoto Alson AO. “Profil épidémio-clinique et évolutif des lymphomes malins non hodgkinien vus au service d’oncologie du CHUJRA Antananarivo Madagascar.” Journal of Medical care Research and Review [En ligne]. 2019 [Consulté le 20/01/2021]; 2 (10): [04 pages]. Consultable à l’URL: https://core.ac.uk/download/pdf/233889320.pdf.

Drouet F, Cahu X, Pointreau Y, Denis F, Mahé MA. “Lymphomes malins non hodgkiniens.” EMC Cancer/Radiothérapie. 2010 Novembre; 14(1): 210-229. DOI: https://doi.org/10.1016/S1278-3218(10)70025-1.

Bordessoule D. “Objectif ECN : N°316a Lymphomes malins non hodgkiniens. ” France: Université de Limoges; 2016.

Andon A, Vassal G, Hartmann O, Couanet D, Patte C. “Les lymphomes malins non hodgkiniens.” France: Institut Gustave-Roussy; 2004 Janvier.

Brito AB, Reis F, de Souza CA, Vassallo J, and Lima CSP. “Intracranial primary dural diffuse large B-cell lymphoma successfully treated with chemotherapy.” Int J Clin Exp Med. 2014; 7(2): 456–60.

Mohamed T, Bouziane A, Nassar I, Ajana A, Moatassim Billah N. “Exophtalmie bilateral révelatrice d’un lymphoma méningé.” EMC Journal of Neuroradiology. 2016 Mars; 43(2): 128.

Gader G, Badri M, Zouaghi M, Ben Salem M, Bahri K, Zammel I. “Le Lymphome fronto-orbitaire: à propos d’un cas et revue de la littérature.” EMC Neurochirurgie. 2020 Août; 66(4): 321.

Nair R, Arora N, Mallath MK. “Epidemiology of Non-Hodgkin's Lymphoma in India.” International Journal of Cancer Research and Treatment [En ligne]. 2016 Juillet [Consulté le 20/01/2021]; 91 (1): [08 pages]. Consultable à l’URL : https://www.karger.com/Article/Abstract/447577.

Iwamoto FM, Abrey LE. “Primary dural lymphomas: a review.” Neurosurg Focus. 2006; 21(5): E5.


How to Cite
Tien Yu Song, M., Ralitera, A., Rasolofoson, C. U., Bemora, J. S., Rasolonjatovo, E. C., Ratovondrainy, W., Mamiarisoa, R., & Andriamamonjy, C. (2021). Diagnostic Difficulties and Management of Childhood Lymphoma: A Case Report. European Journal of Clinical Medicine, 2(4), 1–3. https://doi.org/10.24018/clinicmed.2021.2.4.70